‘Grey’s Anatomy’ Cast on the Past, Present, and Future of the ABC Drama

For more than 400 episodes, Grey’s Anatomy has followed the personal and professional lives of the doctors, residents, nurses, and patients at Grey + Sloan Memorial Hospital, captivating millions around the world with its curious cases, riveting romances, and more.

“I think originally the draw was that it looked like everywhere in America. It looked like a hospital,” says Chandra Wilson, who plays Dr. Miranda Bailey. “People were drawn to these characters, and the stories were universal stories. And that’s the thing that hasn’t changed.”

In the video above, stars Wilson, Camilla Luddington (Dr. Jo Wilson), and Kim Raver (Dr. Teddy Altman) look back at some of their favorite storylines from the past 20 seasons of television’s longest-running prime-time medical drama—and tease what’s coming up next.

Season 21 of Grey’s Anatomy premieres Thursday, September 26, at 10 p.m. ET/PT on ABC and streams next day on Hulu. All 20 seasons are currently available to stream on Hulu.